Synthetic data were analyzed to determine the most cost-effective tomographic monitoring system for a geologic carbon sequestration injection site. Double-difference tomographic inversion was performed on 125 synthetic data sets: five stages of CO2 plume growth, five seismic event regions, and five geophone arrays. Each resulting velocity model was compared quantitatively to its respective synthetic velocity model to determine accuracy. The results were examined to determine a relationship between cost and accuracy in monitoring, verification, and accounting applications using double-difference-tomography. The geophone arrays with widely varying geophone locations, both laterally and vertically, performed best.