In this article, two experimental runs were chosen in order to apply the ANNi model. In the first run, three experimental points were obtained, where the concentration of the solution of the absorber inlet was increased; at the same time, the value of *Q*_{AB} increased, as shown in Fig. 12(a). The ANNi model was applied for a known value of *Q*_{AB} and the optimal inlet conditions were determined (optimal strategy) as shown in Fig. 12(b). When comparing the ANNi model with the experimental data, a good prediction will be appreciated. Therefore, taking into account the latest experimental data, where operating conditions were *T*_{in.Sol} = 81.61 °C, $x\u02d9$_{in.Sol} = 0.018 kg/s, *T*_{out.Sol} = 99.76 °C, $x\u02d9$_{out.Sol} = 0.01898 kg/s, *T*_{in.Vap} = 60.50 °C, $x\u02d9$_{in.Vap} = 0.00098 kg/s, *X*_{in.AB} = 56.96% (in weight), *X*_{out.AB} = 54.02% (in weight), *P*_{AB} = 20 kPa, and *Q*_{AB} = 1.7722 kW, an ANNi model was applied to analyze the *Q*_{AB} behavior in the function of *X*_{in.AB}, in order to raise the value of *Q*_{AB}, reaching a value of 2.44 kW (improved a 37.7%) when the 59% of concentrated solution was supplied; it must be pointed out that the three values last reached by the model ANNi were out from the experimental data. Furthermore, the relative error of the theoretical *Q*_{AB} with respect to the *Q*_{AB} obtained by the ANNi model has been calculated (see Table 9). The result indicated that when the value of *X*_{in.AB} increased from 56.96 to 58, 58.5, and 59% (the weight of LiBr was increased with respect to H_{2}O), the error was increased from the theoretical value from 17.5 to 27.5%, respectively; these model errors showed a value of 320 and 520 W above the theoretical *Q*_{AB}; it is highly probable that the values found by the ANNi model can be reached, since the results were congruent with the experimental tendency. A certain analysis limit above the experimental interval has been considered, as the mixture LiBr–H_{2}O has crystallization problems that prevent the equipment to function when it was concentrated above 70%.