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Proceedings Papers

Sub-Micron 3D Fluorescent Imaging and Visualization of Remodeling Cavities in Cancellous Bone

Craig R. Slyfield, Ryan E. Tomlinson, Evgeniy V. Tkachenko, Kyle E. Neimeyer, Grant J. Steyer, David L. Wilson, Christopher J. Hernandez
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 21-22, June 25–29, 2008
Paper No: SBC2008-193099
DOI: https://doi.org/10.1115/SBC2008-193099
View Paper titled, Sub-Micron 3D Fluorescent Imaging and Visualization of Remodeling Cavities in Cancellous Bone
Click here to open pdf in another window PDF for Sub-Micron 3D Fluorescent Imaging and Visualization of Remodeling Cavities in Cancellous Bone
Topics: Bone, Cavities, Imaging, Visualization, Mechanical properties, Stress, Biological tissues, Finite element analysis, Materials properties, Microscale devices
Proceedings Papers

The Effects of the Inhibition of Connexin 43 on Pre-Osteoblasts and Their Response to Mechanical Stimulation

Danese M. Joiner, Ethan L. H. Daley, Steven A. Goldstein
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 409-410, June 25–29, 2008
Paper No: SBC2008-192700
DOI: https://doi.org/10.1115/SBC2008-192700
View Paper titled, The Effects of the Inhibition of Connexin 43 on Pre-Osteoblasts and Their Response to Mechanical Stimulation
Click here to open pdf in another window PDF for The Effects of the Inhibition of Connexin 43 on Pre-Osteoblasts and Their Response to Mechanical Stimulation
Topics: Osteoblasts, Bone, Fluids, Junctions, Shear stress, Gravity (Force), Stress
Proceedings Papers

Parametric Finite Element Analysis of Physical Stimuli Resulting From Mechanical Stimulation of Tissue Engineered Cartilage

Omotunde M. Babalola, Lawrence J. Bonassar
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 91-92, June 25–29, 2008
Paper No: SBC2008-192633
DOI: https://doi.org/10.1115/SBC2008-192633
View Paper titled, Parametric Finite Element Analysis of Physical Stimuli Resulting From Mechanical Stimulation of Tissue Engineered Cartilage
Click here to open pdf in another window PDF for Parametric Finite Element Analysis of Physical Stimuli Resulting From Mechanical Stimulation of Tissue Engineered Cartilage
Topics: Biological tissues, Cartilage, Finite element analysis, Maintenance, Chondrocytes, Density, Osteoblasts, Patient treatment, Stem cells, Tissue engineering
Proceedings Papers

Micromotions at the Bone Implant Interface Up-Regulate Osteoblasts-Mediated Activation of Osteoclasts in Ex Vivo Human Samples

Vincent A. Stadelmann, Dominique P. Pioletti
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 865-866, June 20–24, 2007
Paper No: SBC2007-175743
DOI: https://doi.org/10.1115/SBC2007-175743
View Paper titled, Micromotions at the Bone Implant Interface Up-Regulate Osteoblasts-Mediated Activation of Osteoclasts in Ex Vivo Human Samples
Click here to open pdf in another window PDF for Micromotions at the Bone Implant Interface Up-Regulate Osteoblasts-Mediated Activation of Osteoclasts in Ex Vivo Human Samples
Topics: Bone, Osteoblasts, Biological tissues, Arthroplasty, Prostheses, Risk
Proceedings Papers

Tissue Strain Transduction and Amplification at the Osteocyte as a Result of Microstructural Changes in the Bone Matrix

Amber Rath Bonivtch, Lynda F. Bonewald, Daniel P. Nicolella
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 893-894, June 20–24, 2007
Paper No: SBC2007-176139
DOI: https://doi.org/10.1115/SBC2007-176139
View Paper titled, Tissue Strain Transduction and Amplification at the Osteocyte as a Result of Microstructural Changes in the Bone Matrix
Click here to open pdf in another window PDF for Tissue Strain Transduction and Amplification at the Osteocyte as a Result of Microstructural Changes in the Bone Matrix
Topics: Biological tissues, Bone, Deformation, Flow (Dynamics), Fluids, Hydrostatic pressure, Osteoblasts, Shear stress, Strain gages
Proceedings Papers

Investigation of Osteoclast Resorption Mechanisms in a Hybrid Cellular Automaton Model of Bone Remodeling

Charles L. Penninger, Ryan K. Roeder, Glen L. Niebur, John E. Renaud
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 351-352, June 20–24, 2007
Paper No: SBC2007-176171
DOI: https://doi.org/10.1115/SBC2007-176171
View Paper titled, Investigation of Osteoclast Resorption Mechanisms in a Hybrid Cellular Automaton Model of Bone Remodeling
Click here to open pdf in another window PDF for Investigation of Osteoclast Resorption Mechanisms in a Hybrid Cellular Automaton Model of Bone Remodeling
Topics: Bone, Robots, Biological tissues, Damage, Maintenance, Minerals, Osteoblasts, Stress
Proceedings Papers

Microvascular Oreintation During Angiogenesis: Effects of Mechanical Stretch and Boundary Conditions

Laxminarayanan Krishnan, Clayton J. Underwood, Steve A. Maas, Benjamin Ellis, Tejas C. Kode, James B. Hoying, Jeffrey A. Weiss
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1033-1034, June 20–24, 2007
Paper No: SBC2007-176598
DOI: https://doi.org/10.1115/SBC2007-176598
View Paper titled, Microvascular Oreintation During Angiogenesis: Effects of Mechanical Stretch and Boundary Conditions
Click here to open pdf in another window PDF for Microvascular Oreintation During Angiogenesis: Effects of Mechanical Stretch and Boundary Conditions
Topics: Boundary-value problems, Endothelial cells, Chondrocytes, Cordage, Fibers, Fibroblasts, Muscle, Osteoblasts, Vessels
Proceedings Papers

Analysis of the Active Response of Cells to Cyclic Loading Using a Modified AFM System

P. Weafer, N. Reynolds, W. Ronan, E. Dowling, S. Jarvis, P. McGarry
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT35A005, June 26–29, 2013
Paper No: SBC2013-14793
DOI: https://doi.org/10.1115/SBC2013-14793
View Paper titled, Analysis of the Active Response of Cells to Cyclic Loading Using a Modified AFM System
Click here to open pdf in another window PDF for Analysis of the Active Response of Cells to Cyclic Loading Using a Modified AFM System
Topics: Atomic force microscopy, Deformation, Biological tissues, Maintenance, Osteoblasts, Tension, Testing
Proceedings Papers

Primary Cilia Knockdown Reduces the Number of Stromal Cells in Three Dimensional Ex Vivo Culture

Thomas R. Coughlin, Matthew Haugh, Muriel Voisin, Evelyn Birmingham, Laoise M. McNamara, Glen L. Niebur
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT50A006, June 26–29, 2013
Paper No: SBC2013-14723
DOI: https://doi.org/10.1115/SBC2013-14723
View Paper titled, Primary Cilia Knockdown Reduces the Number of Stromal Cells in Three Dimensional Ex Vivo Culture
Click here to open pdf in another window PDF for Primary Cilia Knockdown Reduces the Number of Stromal Cells in Three Dimensional Ex Vivo Culture
Topics: Bone, Osteoblasts, Signals, Stem cells
Proceedings Papers

Murine Osteochondral Stem Cells Express Collagen Type I More Strongly on PDMS Substrates Than on Tissue Culture Plastic

William S. Van Dyke, Ozan Akkus, Eric Nauman
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT17A008, June 26–29, 2013
Paper No: SBC2013-14272
DOI: https://doi.org/10.1115/SBC2013-14272
View Paper titled, Murine Osteochondral Stem Cells Express Collagen Type I More Strongly on PDMS Substrates Than on Tissue Culture Plastic
Click here to open pdf in another window PDF for Murine Osteochondral Stem Cells Express Collagen Type I More Strongly on PDMS Substrates Than on Tissue Culture Plastic
Topics: Biological tissues, Plasma desorption mass spectrometry, Stem cells, Stiffness, Osteoblasts, Bone, Anchorage, Chondrocytes, Fibers, Stress
Proceedings Papers

Fluid-Structure Interaction Modelling Predicts That Strain Transfer Through Focal Attachments of Osteoblast Cells are the Primary Mediators of Mechanical Stimulation Under Fluid Flow

T. J. Vaughan, M. G. Haugh, L. M. McNamara
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT09A012, June 26–29, 2013
Paper No: SBC2013-14259
DOI: https://doi.org/10.1115/SBC2013-14259
View Paper titled, Fluid-Structure Interaction Modelling Predicts That Strain Transfer Through Focal Attachments of Osteoblast Cells are the Primary Mediators of Mechanical Stimulation Under Fluid Flow
Click here to open pdf in another window PDF for Fluid-Structure Interaction Modelling Predicts That Strain Transfer Through Focal Attachments of Osteoblast Cells are the Primary Mediators of Mechanical Stimulation Under Fluid Flow
Topics: Fluid dynamics, Fluid structure interaction, Modeling, Osteoblasts, Bone, Flow (Dynamics), Fluids, Physiology
Proceedings Papers

Osteocytes in Bone Can Regulate the Turnover of Adjacent Mineralized Growth Plate Cartilage

Lieke G. E. Cox, Corrinus C. van Donkelaar, Bert van Rietbergen, Rik Huiskes, Keita Ito
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 53-54, June 17–21, 2009
Paper No: SBC2009-206251
DOI: https://doi.org/10.1115/SBC2009-206251
View Paper titled, Osteocytes in Bone Can Regulate the Turnover of Adjacent Mineralized Growth Plate Cartilage
Click here to open pdf in another window PDF for Osteocytes in Bone Can Regulate the Turnover of Adjacent Mineralized Growth Plate Cartilage
Topics: Bone, Cartilage, Osteoblasts, Junctions, Linings (Textiles)
Proceedings Papers

Calcium Signaling in Bone Cell Networks Induced by Fluid Flow

X. Lucas Lu, Bo Huo, Andrew D. Baik, X. Edward Guo
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 291-292, June 17–21, 2009
Paper No: SBC2009-206043
DOI: https://doi.org/10.1115/SBC2009-206043
View Paper titled, Calcium Signaling in Bone Cell Networks Induced by Fluid Flow
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Topics: Bone, Fluid dynamics, Osteoblasts, Junctions, Oscillations, Printing, Self-assembly
Proceedings Papers

Alteration of Bone’s Nonlinear Elastic and Viscoelastic Nanomechanical Properties Is Triggered by Low Intensity Pulsed Ultrasound

Suzanne Ferreri, Yi-Xian Qin
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 45-46, June 17–21, 2009
Paper No: SBC2009-206711
DOI: https://doi.org/10.1115/SBC2009-206711
View Paper titled, Alteration of Bone’s Nonlinear Elastic and Viscoelastic Nanomechanical Properties Is Triggered by Low Intensity Pulsed Ultrasound
Click here to open pdf in another window PDF for Alteration of Bone’s Nonlinear Elastic and Viscoelastic Nanomechanical Properties Is Triggered by Low Intensity Pulsed Ultrasound
Topics: Ultrasound, Signals, Bone, Biological tissues, Fracture (Materials), Fracture (Process), Nanoscale phenomena, Strength (Materials), Viscoelasticity, Materials properties
Proceedings Papers

Bone Marrow Adipogenesis Is Affected by Insulin-Like Growth Factor-1 Complexes

J. Christopher Fritton, Yuki Kawashima, Hui Sun, Yingjie Wu, Wilson Mejia, Hayden W. Courtland, Clifford J. Rosen, Shoshana Yakar
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 569-570, June 17–21, 2009
Paper No: SBC2009-206158
DOI: https://doi.org/10.1115/SBC2009-206158
View Paper titled, Bone Marrow Adipogenesis Is Affected by Insulin-Like Growth Factor-1 Complexes
Click here to open pdf in another window PDF for Bone Marrow Adipogenesis Is Affected by Insulin-Like Growth Factor-1 Complexes
Topics: Bone, Biological tissues, Maintenance, Osteoblasts, Stem cells
Proceedings Papers

Biopolymer Polyelectrolyte Complex Nanocomposites for Bone Tissue Engineering

Devendra Verma, Kalpana Katti, Dinesh Katti
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 1185-1186, June 17–21, 2009
Paper No: SBC2009-206390
DOI: https://doi.org/10.1115/SBC2009-206390
View Paper titled, Biopolymer Polyelectrolyte Complex Nanocomposites for Bone Tissue Engineering
Click here to open pdf in another window PDF for Biopolymer Polyelectrolyte Complex Nanocomposites for Bone Tissue Engineering
Topics: Biopolymers, Bone, Nanocomposites, Adhesion, Porosity, Biocompatibility, Biodegradation, Biological tissues, Fibers, Osteoblasts
Proceedings Papers

A Semi-3D Real-Time Imaging Technique for Measuring Bone Cell Deformation Under Fluid Flow

Andrew D. Baik, X. Lucas Lu, Bo Huo, X. Sherry Liu, Cheng Dong, X. Edward Guo
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 823-824, June 17–21, 2009
Paper No: SBC2009-206524
DOI: https://doi.org/10.1115/SBC2009-206524
View Paper titled, A Semi-3D Real-Time Imaging Technique for Measuring Bone Cell Deformation Under Fluid Flow
Click here to open pdf in another window PDF for A Semi-3D Real-Time Imaging Technique for Measuring Bone Cell Deformation Under Fluid Flow
Topics: Bone, Deformation, Fluid dynamics, Imaging, Adhesion, Flow (Dynamics), Fluids, Microscopy, Osteoblasts, Shear (Mechanics)
Proceedings Papers

Mechanotransductive Effects of Acoustic Radiation Force on Osteoblastic Primary Cilium, Cytoskeleton and Ca 2+ Influx

Y. X. Qin, S. Zhang, J. Cheng
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 39-40, June 20–23, 2012
Paper No: SBC2012-80582
DOI: https://doi.org/10.1115/SBC2012-80582
View Paper titled, Mechanotransductive Effects of Acoustic Radiation Force on Osteoblastic Primary Cilium, Cytoskeleton and Ca 2+ Influx
Click here to open pdf in another window PDF for Mechanotransductive Effects of Acoustic Radiation Force on Osteoblastic Primary Cilium, Cytoskeleton and Ca 2+ Influx
Topics: Acoustics, Radiation (Physics), Ultrasound, Bone, Signals, Biological tissues, Bone fractures, Osteoblasts, Temperature, Transients (Dynamics)
Proceedings Papers

Comparison of Mechanosensitivity of Human Primary-Cultured Osteoblast Cells and Human Osteosarcoma Cell Line Under Hydrostatic Pressure

Yasaman Ganji, Mehran Kasra
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 825-826, June 20–23, 2012
Paper No: SBC2012-80030
DOI: https://doi.org/10.1115/SBC2012-80030
View Paper titled, Comparison of Mechanosensitivity of Human Primary-Cultured Osteoblast Cells and Human Osteosarcoma Cell Line Under Hydrostatic Pressure
Click here to open pdf in another window PDF for Comparison of Mechanosensitivity of Human Primary-Cultured Osteoblast Cells and Human Osteosarcoma Cell Line Under Hydrostatic Pressure
Topics: Hydrostatic pressure, Osteoblasts, Bone, Pressure, Primary cells, Patient treatment
Proceedings Papers

Thermal Effects on Osteogenesis of Human Mesenchymal Stem Cells

Jing Chen, Sihong Wang
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 309-310, June 20–23, 2012
Paper No: SBC2012-80885
DOI: https://doi.org/10.1115/SBC2012-80885
View Paper titled, Thermal Effects on Osteogenesis of Human Mesenchymal Stem Cells
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Topics: Stem cells, Temperature effects, Heat, Osteoblasts, Bone, Hydrogels, Maintenance, Osteoarthritis, Patient treatment, Self-assembly