... 12 2011 21 12 2011 biomechanics bone composite materials elastic moduli failure (mechanical) fracture molecular biophysics molecular configurations nanomedicine proteins X-ray diffraction mineral crystal degree of orientation nanostructural strength X-ray diffraction...

.... The chondroitin sulfate chains are attached to the proteoglycan core proteins, most of which are attached to hyaluronic acid polymers. As we argued above, despite the fact that the chondroitin sulfate chains belonging to neighboring proteoglycans overlap, they do not significantly impede the motion...

... 09 09 2011 14 10 2011 biological tissues biomechanics elastomers proteins anisotropy heterogeneous inverse mechanics soft tissues biaxial testing Load-bearing tissues (e.g., ligament, heart valve leaflet) are dependent on their underlying structures for proper...

...-dimensional studies have shown that dynamic flow conditions (e.g., pulsatile oscillatory waveforms) elicit an enhanced mechanotransductive response and elevated expression of osteoblastic proteins relative to steady flow. However, dynamic perfusion of three-dimensional scaffolds has been primarily examined...

... processing neurophysiology proteins stress-strain relations microstructure extracellular matrix two-photon sclera glaucoma multiphoton According to the World Health Organization, glaucoma is estimated to affect 80 × 10 6 people by 2020 worldwide, making it the second leading cause...

... 04 10 2011 04 10 2011 biochemistry biomechanics bone failure (mechanical) mechanical stability molecular biophysics muscle prosthetics proteins surgery tissue engineering insertion site autograft central-third patellar tendon natural healing Tendon injury...

... to model and predict the behavior under any load. Most ex vivo tests are performed within 24 h of dissection, so the tissue is still “alive.” For large elastic arteries; however, the passive mechanical behavior is attributed mostly to the very stable proteins, elastin, and collagen. If the testing...

... blood vessels molecular biophysics physiological models proteins tissue engineering The goal of small diameter vessel tissue engineering (SVTE) is to create functional living tissue equivalents with mechanical properties that ideally resemble those of native arteries. Commonly, the SVTE...

... polarimetry proteins tensile strength preconditioning vector correlation facet capsular ligament fiber realignment cyclic loading Biological specimens exhibit a time dependence during mechanical testing that is generally characterized by a decrease in the load produced at a given...

... properties of the two main, passive, load-bearing components of the artery wall, elastin, and collagen. Elastin matrix proteins are modeled with an orthotropic neo-Hookean material. High stretch behavior is governed by an orthotropic crimped fiber material modeled as a planar sinusoidal linear elastic beam...

... tissues biomechanics cellular biophysics deformation dissolving molecular biophysics physiological models proteins In the mathematical framework of continuum growth theories, two fundamental modes of growth are recognized: volumetric or interstitial growth and surface or appositional growth...

... (governing the speed of the local reorientation of collagen fibers toward the direction of maximum stiffness). biomechanics cellular biophysics gels molecular biophysics proteins Collagen is an important protein in the human body, and it is a major constituent in, e.g., bone, cartilage...

... for the gap distance to decrease to asperity size. For realistic physiological parameters, the time for the surfaces to contact is a minimum of several minutes and likely much longer. The role of albumin in the synovial fluid is included because the large protein molecules are trapped by the small openings...

... tissues biomechanics elastic constants elasticity finite element analysis internal stresses molecular biophysics orthopaedics proteins 22 10 2009 19 12 2009 18 01 2010 22 04 2010 22 04 2010 2010 American Society of Mechanical Engineers ...

... molecular biophysics physiological models proteins swelling triphasic theory cartilage curling inhomogeneity fixed charge density Osmotic pressure is critical for the development of biological tissues and the maintenance of normal functions. In the early development of limb, mesenchymal...

... moduli hardness mechanical stability molecular biophysics nanoindentation proteins viscoelasticity nanoindentation creep viscoelasticity viscosity bone matrix Bone is a viscoelastic material in which mechanical properties change over the duration of loading ( 1 2 ). Creep...

....3850 28 11 2007 29 05 2009 05 01 2010 05 01 2010 biological organs biological tissues biomechanics biomedical MRI biorheology diagnostic radiography obstetrics proteins soft tissue mechanics cervical tissue cervical insufficiency rheological model...

... the expression of alkaline phosphatase (ALP) at the protein- and mRNA levels, as well as for calcium accumulation. The timing of HP stimulation affected hMSC proliferation and expression of ALP activity. HP stimulation after 6 days was most effective at promoting ALP activity. CS-containing matrices promoted...

... apparent elastic modulus at an indentation strain of 30% from AFM measurements for each region and age correlated well with the long-term elastic modulus measured from 30% unconfined compression tests (slope not significantly different from 1, p > 0.05 ). Protein, lipid, and sulfated glycosaminoglycan...

... model constitutive modeling biological tissues biomechanics molecular biophysics proteins tensile testing 2009 American Society of Mechanical Engineers ...